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SRP6161 Sigma-Aldrich

FGF-7 human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

Synonym: Fibroblast growth factor 7, HBGF-7, Heparin-binding growth factor 7, KGF, Keratinocyte growth factor

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Properties

Related Categories Cell Culture, FGF-4 to FGF-8, Fibroblast Growth Factors (FGF), Growth Factors and Cytokines, Reagents and Supplements More...
biological source   human
recombinant   expressed in human cells
assay   ≥95% (SDS-PAGE)
form   lyophilized
mol wt   mol wt (17 and 30 kDa, monomer, glycosylated)
packaging   pkg of 10 μg
NCBI accession no.   P21781
UniProt accession no.   P21781
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... FGF7(2252)

Description

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Physical form

Lyophilized from a PBS solution.

Biochem/physiol Actions

Fibroblast growth factor (FGF) family members are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. This protein associates with and activates fibroblast growth factor receptors (FGFRs). Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.

General description

Fibroblast growth factor-7 (FGF-7) is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities. The gene encoding this protein is localized on human chromosome 15q21.1.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


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Cell Culture Guide
Protocols & Articles

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Peer-Reviewed Papers
15

References

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