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SRP6163 Sigma-Aldrich

FLT-3 Ligand human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Synonym: CD135, FLK2, Fms-related tyrosine kinase 3 ligand, STK1, Stem cell tyrosine kinase 1

  •  NACRES NA.32

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Properties

Related Categories Cell Culture, Growth Factors and Cytokines, Hematopoietic Cytokines, Reagents and Supplements, Recombinant Flt ligands More...
biological source   human
recombinant   expressed in HEK 293 cells
assay   ≥95% (SDS-PAGE)
form   lyophilized
mol wt   24-30 kDa (monomer, glycosylated)
packaging   pkg of 10 μg
application(s)   cell culture | mammalian: suitable
NCBI accession no.   P36888
UniProt accession no.   P36888
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... FLT3(2322)

Description

General description

FLT3 ligand is a receptor for the Flt3 cytokine and has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation. Human flt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells.

Physical form

Lyophilized from a PBS solution.

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

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