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SRP6218 Sigma-Aldrich

FGF-6 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Synonym: FGFG, Fibroblast Growth Factor-6, HBGF-6

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Properties

Related Categories Cell Culture, FGF-4 to FGF-8, Fibroblast Growth Factors (FGF), Growth Factors and Cytokines, Reagents and Supplements More...
biological source   human
recombinant   expressed in E. coli
assay   ≥95% (SDS-PAGE)
form   lyophilized powder
mol wt   18.7 kDa
packaging   pkg of 10 and 50 μg
impurities   <1 EU/μg endotoxin (LAL test)
UniProt accession no.   P10767
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... FGF6(2251)

Description

General description

FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues.

Physical form

Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Tris, pH 7.5, and 50 mM NaCl.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of ≤0.5 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Cell Culture Guide
Protocols & Articles

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