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SRP6346 Sigma-Aldrich

TREM1 human

recombinant, expressed in E. coli, ≥85% (SDS-PAGE)

Synonym: CD354, TREM-1, Triggering receptor expressed on myeloid cells 1

  •  NACRES NA.32

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Properties

biological source   human
recombinant   expressed in E. coli
assay   ≥85% (SDS-PAGE)
form   liquid
mol wt   23.3 kDa (209 aa, 21-205 aa + His Tag)
packaging   pkg of 100 μg
concentration   0.5 mg/mL
UniProt accession no.   Q9NP99
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... TREM1(54210)

Description

General description

TREM1 is a receptor belonging to the Ig super family that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. Recombinant human TREM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physical form

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 30% glycerol and 1 mM DTT.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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