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SRP6351 Sigma-Aldrich

CD244 human

recombinant, expressed in E. coli, ≥85% (SDS-PAGE)

Synonym: 2B4, CD244 molecule, NAIL, NKR2B4, Nmrk, SLAMF4, natural killer cell receptor 2B4

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Properties

Related Categories CD160 to CD340, Cell Biology, Cell Signaling and Neuroscience, Cluster of Differentiation (CD) Proteins, Cytokines and Growth Factors,
biological source   human
recombinant   expressed in E. coli
assay   ≥85% (SDS-PAGE)
form   liquid
mol wt   25.5 kDa (230 aa, 19-224 aa + His Tag)
packaging   pkg of 50 μg
concentration   0.5 mg/mL
UniProt accession no.   Q9BZW8
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CD244(51744)

Description

General description

CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation in experimental asthma and atopic asthmatics. Functions of CD244 molecules are in eosinophil adhesion and chemotaxis, and correlated the results to the pathophysiology of allergic rhinitis (AR). The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Recombinant human CD244 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Physical form

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea. .

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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