SRP6353 Sigma-Aldrich

CD300A human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym: CD300a molecule, CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H9, CMRF35-H, CMRF35H9, CMRF35H, IGSF12, IRC1/IRC2, IRC1, IRC2, IRp60



Related Categories CD160 to CD340, Cell Biology, Cell Signaling and Neuroscience, Cluster of Differentiation (CD) Proteins, Cytokines and Growth Factors,
biological source   human
recombinant   expressed in E. coli
assay   ≥90% (SDS-PAGE)
form   liquid
mol wt   14.7 kDa (134 aa, 18-128 aa + His Tag)
packaging   pkg of 50 μg
concentration   0.5 mg/mL
UniProt accession no.   Q9UGN4
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CD300a(11314)


General description

CD300A belongs to the CD300 family and contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Recombinant human CD300A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physical form

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol and 1 mM DTT.

Safety & Documentation

Safety Information

NONH for all modes of transport


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