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SRP6379 Sigma-Aldrich

CD87 human

recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE)

Synonym: CD87, MO3

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Properties

Related Categories CD55 to CD155, Cell Biology, Cell Signaling and Neuroscience, Cluster of Differentiation (CD) Proteins, Cytokines and Growth Factors,
biological source   human
recombinant   expressed in HEK 293 cells
assay   ≥92% (SDS-PAGE)
form   lyophilized
mol wt   calculated mol wt 32.1 kDa
  observed mol wt 44-48 kDa (DTT-reduced. Protein migrates due to glycosylation. Leu 23 is the predicted N-terminus.)
packaging   pkg of 20 and 100 μg
conjugate   6-His tagged (C-terminus)
UniProt accession no.   Q03405
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... PLAUR(5329)

Description

General description

Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR act as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

Physical form

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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