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SRP6380 Sigma-Aldrich

CD360/IL21R human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Synonym: NILR

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Properties

biological source   human
recombinant   expressed in HEK 293 cells
assay   ≥95% (SDS-PAGE)
form   lyophilized
mol wt   calculated mol wt 25.8 kDa
  observed mol wt 42-50 kDa (DTT-reduced. Protein migrates due to glycosylation. Cys 20 is the predicted N-terminus.)
packaging   pkg of 100 μg
  pkg of 20 μg
conjugate   6-His tagged (C-terminus)
UniProt accession no.   Q9HBE5 
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... IL21R(50615)

Description

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Physical form

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

General description

Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles
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