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SRP6560 Sigma-Aldrich

Wnt-2 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym: INT1L1, IRP, Int-1-like protein 1, Int-1-related protein

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Properties

Related Categories Cell Culture, Growth Factors and Cytokines, Reagents and Supplements, Wnt/β-catenin
biological source   human
recombinant   expressed in E. coli
assay   ≥90% (SDS-PAGE)
form   lyophilized
mol wt   mol wt 39.9 kDa
packaging   pkg of 1 mg
  pkg of 10 μg
  pkg of 50 μg
UniProt accession no.   P09544
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... WNT2(7472)

Description

Reconstitution

Reconstitute in sterile ddH2O to a concentration ≥ 100 μg/mL.

Physical form

Lyophilized without additives.

Biochem/physiol Actions

Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt family member-2 (Wnt-2) has a role in activating β-catenin. It has been shown to have a role in cardiogenesis. The protein is overexpressed in tumors and cancers.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


Cell Culture Guide
Protocols & Articles

Articles

Wnt/β-Catenin Signaling

Background Wnt Signaling Components    a) Wnt protein      b) Receptors of Wnt proteins    c) Wnt signaling modulators Wnt /beta-catenin signaling mechanism    a) Wnt signaling – Off    b) Wnt signal...
Keywords: Adhesion, Apoptosis, Cancer, Cell division, Cell proliferation, Clinical, Degradations, Gene expression, Hormones, Ligands, Metabolism, Phosphorylations, Transcription, Transduction, Ubiquitinations

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Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

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