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T0632 Sigma

Sodium thioglycolate

≥96.5% (iodometric)

Synonym: Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt

  • CAS Number 367-51-1

  • Linear Formula HSCH2COONa

  • Molecular Weight 114.10

  •  Beilstein Registry Number 4569109

  •  EC Number 206-696-4

  •  MDL number MFCD00043386

  •  PubChem Substance ID 24899901

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates P-Z, Monosaccharide More...
InChI Key   GNBVPFITFYNRCN-UHFFFAOYSA-M
assay   ≥96.5% (iodometric)
mp   >300 °C(lit.)
storage temp.   −20°C

Description

Caution

At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

Packaging

25, 100, 500 g in poly bottle

Biochem/physiol Actions

Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3335
WGK Germany 
1
RTECS 
AI7700000

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Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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