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T1330 Sigma-Aldrich

Tamsulosin hydrochloride

≥98% (HPLC)

Synonym: 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride

  • CAS Number 106463-17-6

  • Empirical Formula (Hill Notation) C20H28N2O5S · HCl

  • Molecular Weight 444.97

  •  MDL number MFCD00922997

  •  PubChem Substance ID 329826665

  •  NACRES NA.77

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Properties

Related Categories Adrenergics, Antagonists- Adrenergics, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
Quality Level   100
assay   ≥98% (HPLC)
form   white powder
solubility   DMSO: >10 mg/mL
originator   Boehringer Ingelheim
storage temp.   room temp
SMILES string   Cl.CCOc1ccccc1OCCN[C@H](C)Cc2ccc(OC)c(c2)S(N)(=O)=O
InChI   1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1
InChI key   ZZIZZTHXZRDOFM-XFULWGLBSA-N
Gene Information   human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Tamsulosin is an α1A/1D-adrenoceptor antagonist used as a treatment of benign prostatic hypertrophy (BPH). Its activity as an ? blocker also affects the iris, and has led to complications during cataract surgery, a condition called "floppy iris" syndrome.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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