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T1512 Sigma-Aldrich

Tetramisole hydrochloride

phosphatase inhibitor

Synonym: (±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride

  • CAS Number 5086-74-8

  • Empirical Formula (Hill Notation) C11H12N2S · HCl

  • Molecular Weight 240.75

  •  Beilstein/REAXYS Number 4358989

  •  EC Number 225-799-5

  •  MDL number MFCD00005536

  •  PubChem Substance ID 24278725

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Properties

Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, P to Q,
description   alkaline phosphatase inhibitor
InChI Key   LAZPBGZRMVRFKY-UHFFFAOYSA-N
mp   266-267 °C (lit.)

Description

Application

Structure-activity relationship for tetramisole derivatives as alkaline phosphatase inhibitors.

Suitable for inhibition of various mammalian alkaline phosphatases (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited.

Packaging

2, 5, 10 g in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Other Notes

Racemic form of levamisole.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NJ5950000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Development of a Chiral Method for Levamisole and its Metabolite, Aminorex, for Monitoring Abuse in Horse Racing and Cocaine Adulteration

Concern over the abuse of amphetamines and other stimulants goes beyond its prevalence in the human population. Unscrupulous and unethical animal handlers administer drugs to their charges to enhance...
David S Bell, Denise Wallworth
Reporter US Volume 33.4
Keywords: Cardiovascular, Chiral resolution, High performance liquid chromatography, Inflammation, Mass spectrometry, Metabolites, Reductions, Separation

HPLC Chiral Analysis of Levamisole on Astec® Cyclobond® I 2000 DMP

From our library of Articles, Sigma-Aldrich presents HPLC Chiral Analysis of Levamisole on Astec® Cyclobond® I 2000 DMP
Keywords: Chromatography, High performance liquid chromatography

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