• USA Home
  • T2501 - L-Thyroxine sodium salt pentahydrate

EMAIL THIS PAGE TO A FRIEND
T2501 Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

≥98% (HPLC), powder

Synonym: 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

  • CAS Number 6106-07-6

  • Linear Formula HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O

  • Molecular Weight 888.93

  •  Beilstein/REAXYS Number 5721845

  •  EC Number 200-221-4

  •  MDL number MFCD00149110

  •  PubChem Substance ID 24900041

  •  NACRES NA.32

Purchase

Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones,
Quality Level   200
biological source   synthetic (organic)
assay   ≥98% (HPLC)
form   powder
mp   207-210 (dec.) (lit.)
solubility   4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow
shipped in   ambient
storage temp.   −20°C
SMILES string   O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O
InChI   1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1
InChI key   JMHCCAYJTTWMCX-QWPJCUCISA-M
Gene Information   mouse ... Cnr2(12802)
rat ... Cnr1(25248)

Description

Packaging

1, 5 g in glass bottle

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Preparation Note

L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
YP2833760
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

T0397 L-Thyroxine sodium salt pentahydrate, γ-irradiated, powder, BioXtra, suitable for cell culture
92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?