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T2528 Sigma-Aldrich

Terbutaline hemisulfate salt

Synonym: 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol, 5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol hemisulfate salt

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Properties

Related Categories Adrenergics, Adrenergics - Agonists, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index,
Quality Level   100
solubility   H2O: soluble 100 mg/mL, clear to slightly hazy, colorless to yellow
originator   Novartis
SMILES string   OS(O)(=O)=O.CC(C)(C)NCC(O)c1cc(O)cc(O)c1.CC(C)(C)NCC(O)c2cc(O)cc(O)c2
InChI   1S/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)
InChI key   KFVSLSTULZVNPG-UHFFFAOYSA-N
Gene Information   human ... ADRB1(153), ADRB2(154), ADRB3(155)

Description

Application

Terbutaline hemisulfate has been used as a reference standard for the determination of β agonist residues in meat4. It has also been used as a standard for developing LC-MS-MS based techniques for the analysis of veterinary drugs5.

Packaging

1, 5 g in poly bottle

Biochem/physiol Actions

Terbutaline is a β-adrenoceptor agonist and is known to function as a bronchodilator. Studies have reported that terbutaline is potent inhibitor of premature labor6.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Terbutaline hemisulfate salt dissolves in water at 100 mg/ml to yield a colorless to yellow, clear to slightly hazy solution.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
DN9000000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Terbutaline Enantiomers on Astec® CHIROBIOTIC® T

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Terbutaline Enantiomers on Astec® CHIROBIOTIC® T
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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