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T3577 Sigma

Tolperisone hydrochloride

≥98% (HPLC), solid

Synonym: 2-Methyl-1-(4-methylphenyl)-3-(1-piperidyl)propan-1-one hydrochloride

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels,
InChI Key   ZBUVYROEHQQAKL-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
color   white
solubility   H2O: >20 mg/mL
storage temp.   room temp

Description

Biochem/physiol Actions

Tolperisone is an ion channel blocker and centrally acting muscle relaxant.

Tolperisone regulates ionic currents in myelinates axons and subsequently decreases excitability and mediates its antispastic functions3.

Packaging

50, 250 mg in glass bottle

Preparation Note

Tolperisone hydrochloride dissolves in water at a concentration that is greater than 20 mg/ml.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UH1575500

Documents

Certificate of Analysis

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Ion Channels Research

Ion transport across the relatively impermeable lipid bilayer of the cell membrane is accomplished via membrane proteins known as ion channels, pumps and transporters. Ion channels are gated pores an...
Keywords: Biological processes, Cell signaling, Diseases, Hormones, Ligands, Neurotransmitters

HPLC Analysis of Tolperisone Enantiomers on Astec® CHIROBIOTIC® V2

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tolperisone Enantiomers on Astec® CHIROBIOTIC® V2
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Sodium Channels

Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials. A variety of toxins and chemicals are known to either block or m...
Keywords: Analgesics, Atomic absorption spectroscopy, Central Nervous System, Gene expression, Insecticides, Neurotoxins

Peer-Reviewed Papers
15

References

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