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T5516 Sigma-Aldrich

3,3′,5-Triiodo-L-thyronine sodium salt

γ-irradiated, powder, suitable for, suitable for cell culture

Synonym: Liothyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine sodium salt, T3

  • CAS Number 55-06-1

  • Empirical Formula (Hill Notation) C15H11I3NNaO4

  • Molecular Weight 672.96

  •  Beilstein Registry Number 8179867

  •  EC Number 200-223-5

  •  MDL number MFCD00002594

  •  PubChem Substance ID 24900290

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Properties

Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones,
InChI Key   SBXXSUDPJJJJLC-YDALLXLXSA-M
sterility   γ-irradiated
form   powder
suitability   suitable for
  suitable for cell culture
storage temp.   −20°C
Gene Information   human ... THRA(7067), THRB(7068)
rat ... Thra(81812), Thrb(24831)

Description

Biochem/physiol Actions

T3 is a thyroid hormone that increases rates of proteins synthesis, stimulates the breakdown of cholesterol, and effects embryonic development. In cell culture, T3 regulates cell differentiation and protein expression.

Preparation Note

Package size based on 3,3′,5-Triiodo-L-thyronine sodium salt content; vial may also contain inert salts, such as sodium chloride

Reconstitution

To prepare 20 μg/ml stock solution: add 1 ml 1 N NaOH; gently swirl to dissolve; add 49 ml sterile medium.

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin


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Cell Culture Guide
Protocols & Articles

Articles

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1
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Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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