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T6205 Sigma-Aldrich

TPh A

≥98% (HPLC)

Synonym: N-{[4-(Benzyloxy)phenyl](methyl)-γ4-sulfanylidene}-4-methylbenzenesulfonamide, S-[p-(Benzyloxy)phenyl]-S-methyl-N-(p-tolylsulfonyl)-sulfilimine, Triphenyl compound A

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators,
Quality Level   100
assay   ≥98% (HPLC)
form   white powder
solubility   DMSO: >30 mg/mL
storage temp.   2-8°C
SMILES string   Cc1ccc(cc1)S(=O)(=O)N=S(C)c2ccc(OCc3ccccc3)cc2
InChI   1S/C21H21NO3S2/c1-17-8-14-21(15-9-17)27(23,24)22-26(2)20-12-10-19(11-13-20)25-16-18-6-4-3-5-7-18/h3-15H,16H2,1-2H3
InChI key   IMUPOWQOXOCVBN-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

TPh A is an inhibitor of the nuclear protein pirin. TPh A (Triphenyl compound A) inhibits the interaction between Bcl3 oncoprotein and the nuclear protein pirin. TPh A inihibits melanoma cell migration.

Preparation Note

TPh A is soluble in DMSO at a concentration that is greater than 30 mg/ml.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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