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T6515 Sigma-Aldrich

Cholecystokinin Fragment 30-33 Amide

≥95% (HPLC)

Synonym: CCK-4, Gastrin Tetrapeptide, Tetragastrin hydrochloride, Trp-Met-Asp-Phe amide

  • CAS Number 1947-37-1

  • Empirical Formula (Hill Notation) C29H36N6O6S

  • Molecular Weight 596.70

  •  MDL number MFCD00076492

  •  PubChem Substance ID 24900382

  •  NACRES NA.32

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cholecystokinins, Cholecystokinnin - Receptor Agonists,
Quality Level   200
assay   ≥95% (HPLC)
form   powder
application(s)   toxicology assay: suitable
storage temp.   −20°C
SMILES string   CSCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc3ccccc3)C(N)=O
InChI   1S/C29H36N6O6S/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t20-,22-,23-,24-/m0/s1
InChI key   RGYLYUZOGHTBRF-BIHRQFPBSA-N
Gene Information   human ... CCK(885)
rat ... Cckbr(25706)

Description

Amino Acid Sequence

Trp-Met-Asp-Phe-NH2

Application

Cholecystokinin Fragment 30-33 Amide can be used for inactivating the CCK8 antiserum. The product can also be used as an antigen utilized in absorption control for testing the specificity of antisera.

Biochem/physiol Actions

Cholecystokinin Fragment 30-33 Amide also referred to as CCK-4 or Trp-Met-Asp-Phe amide is a peptide fragment derived from peptide hormone cholecystokinin. CCK-4 is a panicogenic agent that induces panic attacks in humans. This property of the compound can be used in scientific research for testing the new anxiolytic drugs.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Cholecystokinin Fragment 30-33 Amide dissolves in Dimethylformamide at 20 mg/ml to yield a clear, colorless to yellow solution.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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