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T7375 Sigma-Aldrich

Thionicotinamide adenine dinucleotide

≥90%

Synonym: Thionicotinamide-DPN

  • CAS Number 4090-29-3

  • Linear Formula C21H27N7O13SP2

  • Molecular Weight 679.49

  •  MDL number MFCD00079609

  •  PubChem Substance ID 24900446

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Cofactors, Enzymes, Inhibitors, and Substrates, Oxidation-Reduction
InChI Key   JFOSDPGFZXVRDA-UHFFFAOYSA-N
assay   ≥90%
storage temp.   −20°C

Description

Application

Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD+ glycohydrolase activity.

Packaging

25, 100 mg in poly bottle

Biochem/physiol Actions

Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD+ kinase. NAD+ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells.

Linkage

Analog of NAD

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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