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T8691 Sigma-Aldrich

Taurine

suitable for cell culture, meets USP testing specifications

Synonym: 2-Aminoethanesulfonic acid

  • CAS Number 107-35-7

  • Linear Formula NH2CH2CH2SO3H

  • Molecular Weight 125.15

  •  Beilstein/REAXYS Number 1751215

  •  EC Number 203-483-8

  •  MDL number MFCD00008197

  •  PubChem Substance ID 24900552

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Properties

Related Categories Amino Acids, Amino acids, Cell Biology, Core Bioreagents, Functional Foods,
Agency/Method   meets USP testing specifications
Quality Level   200
form   crystalline powder
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, tested
color   white
mp   >300 °C (lit.)
SMILES string   NCCS(O)(=O)=O
InChI   1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
InChI key   XOAAWQZATWQOTB-UHFFFAOYSA-N
Gene Information   rat ... Ppm1a(24666)

Description

Application

Taurine has been used:
• as a component of cardiomyocyte dissociation solution
• as a supplement for modified synthetic oviduct fluid (m-SOF) medium to culture the presumptive zygotes
• as a constituent of low Ca2+ solution employed in preparation of collagenase B solution for colony dissociation into single cells
• to assess its effect on development of bovine embryos fertilized with different bull semen during in vitro fertilization
• as a component of culture media for derivation of cornea organoids

Packaging

1 kg in poly bottle

25, 100 g in poly bottle

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

Taurine is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys. It controls the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. Taurine also plays a vital role in bile formation and fat digestion. Deficiency of taurine is associated with development of anxiety, hyperactivity, epilepsy and depression.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
WX0175000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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