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T8784 Sigma-Aldrich

Thimerosal

BioXtra, 97-101%

Synonym: 2-(Ethylmercuriomercapto)benzoic acid sodium salt, Ethylmercurithiosalicylic acid sodium salt, Mercury-([o-carboxyphenyl]thio)ethyl sodium salt, Sodium ethylmercurithiosalicylate

  • CAS Number 54-64-8

  • Linear Formula 2-(C2H5HgS)C6H4CO2Na

  • Molecular Weight 404.81

  •  Beilstein/REAXYS Number 8169555

  •  EC Number 200-210-4

  •  MDL number MFCD00013062

  •  PubChem Substance ID 24900561

  •  NACRES NA.21

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Biochemicals and Reagents
Quality Level   200
product line   BioXtra
assay   97-101%
impurities   ≤0.0005% Phosphorus (P)
  ≤0.1% Insoluble matter
mp   234-237 °C (dec.) (lit.)
cation traces   Al: ≤0.001%
  Ca: ≤0.002%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Mg: ≤0.0005%
  NH4+: ≤0.1%
  Pb: ≤0.001%
  Zn: ≤0.0005%
Featured Industry   Diagnostic Assay Manufacturing
Mode of action   enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  fungi
SMILES string   [Na+].CC[Hg]Sc1ccccc1C([O-])=O
InChI   1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
InChI key   RTKIYNMVFMVABJ-UHFFFAOYSA-L

Description

Application

Thimerosal is used as an antibacterial and antifungal. It is used as a topical antiseptic on skin and mucous membranes. It is also used as a preservative in pharmaceuticals as well as research.

Packaging

1, 5, 25 g in glass bottle

Biochem/physiol Actions

Thimerosal is a sulfhydryl (thiol) oxidizing reagent capable of inhibiting a wide range of sulfhydryl-dependent enzymes and proteins such as PI3-kinase-dependent methionine synthase, glutamate transport receptors, and Na++K+ dependent ATPases.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2025 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
482.0 °F - closed cup
Flash Point(C) 
250 °C - closed cup

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Roar Assay Kits for Studies in Lipoprotein Metabolism

This technical article is a compilation of select fluorescence-based activity assays developed by Roar Biomedical now offered through Sigma-Aldrich in kit format. The methods are well-characterized, ...
Robert Brocia
Roar Biomedical, Inc.
Keywords: Addition reactions, Cardiovascular, Chromatography, Clinical, Detection methods, Drug discovery, Esterifications, Gas chromatography, High performance liquid chromatography, Separation, Thin layer chromatography

Protocols

PLTP Activity Assay Protocol

Supplied by Roar Biomedical, Inc Catalog Number MAK108 Storage Temperature 2–8 °C, except where indicated
Keywords: Sample preparations

Peer-Reviewed Papers
15

References

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