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T8941 Sigma-Aldrich

L-Tryptophan

from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Synonym: (S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid

  • CAS Number 73-22-3

  • Empirical Formula (Hill Notation) C11H12N2O2

  • Molecular Weight 204.23

  •  Beilstein Registry Number 86197

  •  EC Number 200-795-6

  •  MDL number MFCD00064340

  •  eCl@ss 32160406

  •  PubChem Substance ID 24900575

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Description

Other Notes

Amino acid precursor of serotonin and melatonin

Packaging

1 kg in poly bottle

10 mg in glass bottle

25, 100 g in poly bottle

Application

L-Tryptophan has been used in PreC media preparation and in cell culture.

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that is associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Cell Culture Guide

Milli-Q® Water Purification Solutions
Protocols & Articles

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Peer-Reviewed Papers
15

References

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