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T9034 SAFC

Taurocholic acid sodium salt hydrate

BioXtra, ≥95% (HPLC)

Synonym: 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Sodium taurocholate hydrate

  • CAS Number 345909-26-4

  • Empirical Formula (Hill Notation) C26H44NNaO7S · xH2O

  • Molecular Weight 537.68 (anhydrous basis)

  •  EC Number 205-653-7

  •  MDL number MFCD00150819

  •  PubChem Substance ID 24278230

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Properties

Related Categories Anionic Detergents, Bile Acid Metabolism, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents,
description   anionic
InChI Key   RDAJAQDLEFHVNR-NEMAEHQESA-M
product line   BioXtra
assay   ≥95% (HPLC)
mol wt   micellar avg mol wt 2100
aggregation number   4
application(s)   detection: suitable
impurities   ≤0.005% Phosphorus (P)
  ≤0.1% Insoluble matter
CMC   3-11 mM (20-25°C)
solubility   H2O: 0.2 M, clear, colorless to faintly yellow
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.01%
  Mg: ≤0.005%
  NH4+: ≤0.1%
  Pb: ≤0.001%
  Zn: ≤0.0005%

Description

Application

Taurocholic acid, a bile acid, may be used in studies of the physiological effects of bile salts on intestinal function and bacterial flora development.

Anionic detergent used for protein solubilization.

Packaging

1, 5, 25, 100 g in poly bottle

Biochem/physiol Actions

Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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