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U21100-HH Sigma-Aldrich

DMT-2′O-TBDMS-rU Phosphoramidite

Synonym: 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-uridine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], DMT-2′-O-TBDMS-rU amidite

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Properties

biological source   non-animal source (no BSE/TSE risk)
InChI Key   SKNLXHRBXYGJOC-ZMHKPELYSA-N
product line   Proligo Reagents
assay   ≥99% (31P-NMR)
  ≥99.0% (reversed phase HPLC)
  conforms (1H-NMR)
  conforms (LC/MS)
form   powder
packaging   pkg of 1 × 100 g U211011-01
  pkg of 1 × 500 g U211051-01
application(s)   oligo synthesis: suitable
impurities   ≤0.3 wt. % water content (Karl Fischer)
  ≤0.5% P(III) Impurities 100-169ppm (31P-NMR)
  ≤0.5% single Impurity (reversed phase HPLC)
  ≤3 wt. % residual Solvent content
color   white to off-white
λ   conforms (UV/VIS Identity)
nucleoside profile   base: uridine
base protecting group: none
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: standard
storage temp.   −20°C
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
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