EMAIL THIS PAGE TO A FRIEND
U3003 Sigma-Aldrich

Uridine

powder, BioReagent, suitable for cell culture

Synonym: 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside

  • CAS Number 58-96-8

  • Empirical Formula (Hill Notation) C9H12N2O6

  • Molecular Weight 244.20

  •  Beilstein/REAXYS Number 754902

  •  EC Number 200-407-5

  •  MDL number MFCD00006526

  •  PubChem Substance ID 24900638

  •  NACRES NA.75

Purchase

Properties

Related Categories Cell Culture, Miscellaneous Reagents and Supplements, Reagents and Supplements More...
Quality Level   200
biological source   synthetic (organic)
product line   BioReagent
assay   ≥99%
form   powder
application(s)   cell culture | mammalian: suitable
mp   163-167 °C (lit.)
solubility   H2O: 50 mg/mL
SMILES string   OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI   1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI key   DRTQHJPVMGBUCF-XVFCMESISA-N
Gene Information   mouse ... Uck1(22245)

Description

General description

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is a substrate for nucleotide synthesis in living organisms by de- novo and salvage pathways.

Application

Uridine has been used:
• as an inhibitor of schwann cell proliferation in rat dorsal root ganglia (DRG) neurons culture
• as a medium supplement for epiblasts culture
• as a component of 5-fluoro-2′-deoxyuridine stock solution used for neuronal culture

Packaging

5, 50 g in poly bottle

Biochem/physiol Actions

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like, treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine induces insulin resistance.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Request a Serum Sample
Protocols & Articles

Articles

HPLC Analysis of Nucleosides on Ascentis® Si (HILIC Mode)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Si (HILIC Mode)
Keywords: Chromatography, High performance liquid chromatography

TLC Analysis of Mycotoxins on HPTLC Silica 60F 254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Mycotoxins on HPTLC Silica 60F 254s
Keywords: Agriculture, Thin layer chromatography

TLC Analysis of Nucleosides on HPTLC Silica 60 F254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Nucleosides on HPTLC Silica 60 F254s
Keywords: Thin layer chromatography

TLC Analysis of Nucleosides on HPTLC pre-coated plate RP-18 WF 254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Nucleosides on HPTLC pre-coated plate RP-18 WF 254s
Keywords: Agriculture, Thin layer chromatography

Related Content

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?