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U4135 Sigma-Aldrich

UBP302

≥98% (HPLC)

Synonym: (αS)-α-amino-3-[(2-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid

  • CAS Number 745055-91-8

  • Empirical Formula (Hill Notation) C15H15N3O6

  • Molecular Weight 333.30

  •  MDL number MFCD06411607

  •  PubChem Substance ID 329827630

  •  NACRES NA.77

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Properties

Related Categories AMPA/Kainate Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: ≥5 mg/mL at 60 °C (with warming for 5 minutes)
storage temp.   −20°C
SMILES string   N[C@@H](CN1C=CC(=O)N(Cc2ccccc2C(O)=O)C1=O)C(O)=O
InChI   1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-3-1-2-4-10(9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1
InChI key   UUIYULWYHDSXHL-NSHDSACASA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

UBP302 is a selective GluR5 antagonist. UBP302 is the active enantiomer of UB296 and is one of the most potent GluR5 antagonists available for research use.

Preparation Note

UBP302 is soluble in DMSO at a concentration ≥5 mg/ml.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Glutamate Receptors (Ion Channel Family)

The ion channel family of glutamate receptors ("€œionotropic"€ glutamate receptors or iGluR) comprises three major subtypes based on pharmacology and protein structure.
Keywords: Alzheimer Disease, Anticonvulsants, Atomic absorption spectroscopy, Clinical, Gene expression, Ligands, Neurotransmission, Physiological Processes, Schizophrenia

Peer-Reviewed Papers
15

References

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