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U4884 Sigma-Aldrich

Urea

meets USP testing specifications

Synonym: Carbamide, Carbonyldiamide

  • CAS Number 57-13-6

  • Linear Formula NH2CONH2

  • Molecular Weight 60.06

  •  Beilstein/REAXYS Number 635724

  •  EC Number 200-315-5

  •  MDL number MFCD00008022

  •  PubChem Substance ID 24900650

  •  NACRES NA.75

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Properties

Related Categories Analytical/Chromatography, Biochemicals and Reagents, Chaotropic Agents, Denaturation, Pharmacopoeia,
Agency/Method   meets USP testing specifications
Quality Level   200
assay   98.0-102.0%
form   solid
mp   132-135 °C (lit.)
solubility   H2O: soluble 480 g/L at 20 °C
density   1.335 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
SMILES string   NC(N)=O
InChI   1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI key   XSQUKJJJFZCRTK-UHFFFAOYSA-N
Gene Information   human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

Description

Packaging

1 kg in poly bottle

100, 500 g in poly bottle

5 kg in poly drum

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
YR6250000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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