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U5760 Sigma-Aldrich

(4R)-2-Undecyl-4-thiazolidinecarboxylic acid

≥98% (HPLC)

Synonym: 2-Undecylthiazolidine-4(R)-carboxylic acid

  • CAS Number 298186-80-8

  • Empirical Formula (Hill Notation) C15H29NO2S

  • Molecular Weight 287.46

  •  MDL number MFCD18425615

  •  PubChem Substance ID 329827638

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: >5 mg/mL
storage temp.   2-8°C
SMILES string   CCCCCCCCCCCC1N[C@@H](CS1)C(O)=O
InChI   1S/C15H29NO2S/c1-2-3-4-5-6-7-8-9-10-11-14-16-13(12-19-14)15(17)18/h13-14,16H,2-12H2,1H3,(H,17,18)/t13-,14?/m0/s1
InChI key   FNBSOIBCKUUVJJ-LSLKUGRBSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

BML-241 is a S1P3 (shingosine-1-phosphate receptor) specific antagonist. Treatment with 10 uM BML-241 results in a 40% inhibition of Ca influx in HeLa cells.

Features and Benefits

This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

(4R)-2-Undecyl-4-thiazolidinecarboxylic acid is soluble in DMSO at a concentration that is >5 mg/ml.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Lysophospholipid Receptors

Although historically considered as intermediates in the biosynthesis of glycerophospholipids and the degradation of sphingolipids, the lysophospholipids lysophosphatidic acid (LPA) and sphingosine 1...
Keywords: Atomic absorption spectroscopy, Cancer, Chemical biology, Degradations, Gene expression, Genetic, Genetics, Ligands, Phosphorylations, Transduction

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