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UC166 Sigma-Aldrich

Sulfaphenazole

≥98% (HPLC)

Synonym: 4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide

  • CAS Number 526-08-9

  • Empirical Formula (Hill Notation) C15H14N4O2S

  • Molecular Weight 314.36

  •  EC Number 208-384-3

  •  MDL number MFCD00057226

  •  PubChem Substance ID 24724643

  •  NACRES NA.77

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Drug and Xenobiotic Metabolism, Multi-Drug Resistance and Drug Metabolism, Substrates, Inducers, Inhibitors More...
Quality Level   100
assay   ≥98% (HPLC)
color   white to light yellow
mp   179-183 °C
storage temp.   2-8°C
SMILES string   Nc1ccc(cc1)S(=O)(=O)Nc2ccnn2-c3ccccc3
InChI   1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2
InChI key   QWCJHSGMANYXCW-UHFFFAOYSA-N
Gene Information   human ... CYP2C18(1562), CYP2C19(1557), CYP2C9(1559)

Description

Packaging

5, 10 mg in glass bottle

Biochem/physiol Actions

Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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