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UPS1 Sigma-Aldrich

Universal Proteomics Standard Set

Protein Mass Spectrometry Calibration Standard



Related Categories Mass Spectrometry, Molecular Biology, Peptide and Protein Standards for Mass Spectrometry Analysis, Proteomics, Universal Proteomic Standard More...
Quality Level   200
quality   Protein Mass Spectrometry Calibration Standard
storage temp.   −20°C


General description

The Universal Proteomics Standard (UPS) Set was developed in collaboration with the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG). This protein mixture was extensively evaluated and reported under the direction of ABRF′s sPRG during a comprehensive 2005/2006 study. The findings of the study were presented at the ABRF 2006 and US HUPO 2006 conferences.


The Universal Proteomics Standard (UPS) Set is intended to standardize and/or evaluate mass spectrometric (e.g., LC-MS/MS, MALDI-TOF-MS, etc.) and electrophoretic analysis conditions prior to the analysis of complex protein samples. Potential uses include:
• Bracketing critical experimental datasets for confirming the robustness of analysis methods
• Comparison of MS or other proteomic data that are generated in different labs using a variety of analytical strategies and instruments
• Identifying limitations of proteomics analysis systems and search algorithms
• An external reference to assist with the evaluation of data derived from poorly defined samples

Features and Benefits

Discover the Benefits for Yourself!
• Test the power of your analytical strategy
• Troubleshoot and optimize your analytical protocol
• Confirm system suitability before analyzing critical samples
• Normalize analytical results day to day or lab to lab

Kit component also available separately


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Trypsin from porcine pancreas, Proteomics Grade, BioReagent, Dimethylated 20 μg SDS T6567
Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Protocols & Articles


Universal Proteomics Standards – Validating the Future of Proteomics

The era of high-throughput proteomics has recently blossomed due in large part to advances in the methods by which proteins and proteomes are analyzed. Improved fractionation techniques, combined wit...
LSI Issue 24
Keywords: Amino acid analysis, Fractionation, High performance liquid chromatography, Mass spectrometry, Methods, Newsletters, PAGE, Proteomics, Protocols, Purification, Search, Separation, Support

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Stable Isotope-labeled MS Internal Standards

What happens when you combine state-of-the-art technology with scientific prowess? Full-length protein standards with the highest purity and isotopic incorporation in the industry. Stable isotope-lab...
Keywords: Atomic absorption spectroscopy, Buffers, Digestions, Mass spectrometry, PAGE, Phosphorylations, Proteomics

Peer-Reviewed Papers


Related Products

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UPS2 Proteomics Dynamic Range Standard Set, Protein Mass Spectrometry Calibration Standard
MSQC1 MS Qual/Quant QC Mix, Proteomics MRM LC-MS Calibration Standard Parent proteins in MSQC1 are all present in UPS1.
92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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