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X1126 Sigma-Aldrich

Xylazine

≥99%

Synonym: 2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride

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Properties

Related Categories Adrenergics, Adrenergics - Agonists, Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
Quality Level   200
assay   ≥99%
storage temp.   −20°C
SMILES string   Cc1cccc(C)c1NC2=NCCCS2
InChI   1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)
InChI key   BPICBUSOMSTKRF-UHFFFAOYSA-N

Description

General description

Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions.

Application

Xylazine has been used to anaesthetise experimental animals.

Biochem/physiol Actions

Xylazine when used along with ketamine is considered to be a potent and safe anaesthetic in experimental animal. It is known to elevate the hepatic release of glucose, which aggravates to hyperglycemia.

α2-adrenoceptor agonist, sedative, muscle relaxant.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. X1126.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
XJ0776300
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

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