X6250 Sigma-Aldrich


from marigold

Synonym: α-Carotene-3,3′-diol, β, ε-carotene-3,3′-diol, β, ε-carotene, Lutein

  • CAS Number 127-40-2

  • Empirical Formula (Hill Notation) C40H56O2

  • Molecular Weight 568.87

  •  Beilstein/REAXYS Number 2068547

  •  EC Number 204-840-0

  •  MDL number MFCD08435941

  •  PubChem Substance ID 24902152

  •  NACRES NA.79



Related Categories Allium cepa (Onion), Antioxidant and Free Radical Scavengers, Berberis sp., Cancer Research, Carotenoid,
Quality Level   200
biological source   marigold
form   powder
color   orange to brown
shipped in   dry ice
storage temp.   −70°C
SMILES string   CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C)\C=C\C=C(C)\C=C\[C@H]2C(C)=C[C@H](O)CC2(C)C
InChI   1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36+,37-/m0/s1


General description

Xanthophylls are oxygenated derivatives of carotenoids. It consists of oxygen atoms. Xanthophylls are yellow pigments and are found majorly in the leaves of most green plants.


Xanthophyll has been used:
•  to quantify circulating lutein in birds
•  to study its effect on the synthesis of factor D (FD) by adipocytes
•  for the quantification of carotenoids from the leaves of Brassica oleracea


1, 5 mg in glass bottle

Biochem/physiol Actions

Xanthophyll/Lutein functions as an accessory light-harvesting pigment. It also acts as quenchers of singlet oxygen and chlorophyll triplet states to exhibit protection against photooxidative damage. Xanthophyll is involved in photosynthesis. It has antioxidant properties.

Dietary carotenoid with no vitamin A potency. Increases macular pigment concentration in the eye and may improve visual function.


Dry powder packed under Argon.


Minimum 70% total carotenoids as xanthophyll.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. X6250.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles


Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

HPLC Analysis of Carotene Compounds on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Carotene Compounds on Ascentis® RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Vitamins

Retinoic Acid and Gene Expression

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apopt...
BioFiles 2008, 3.9, 12.
Keywords: Apoptosis, Cancer, Cell proliferation, Cellular processes, Chromatin immunoprecipitation, Condensations, Degradations, Diseases, Gene expression, Hormones, Immunoprecipitation, Ligands, Metabolism, Oxidations, Phosphorylations, Polymerase chain reaction, Sequences, Teratogens, Transcription, Type, Ubiquitinations, Usage, Vitamins

Peer-Reviewed Papers


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