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11022AST Supelco

Astec® CHIROBIOTIC® V Chiral HPLC Column

5 μm particle size, L × I.D. 10 cm × 4.6 mm

  •  eCl@ss 32110501

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Properties

Related Categories Analytical/Chromatography, Astec CHIROBIOTIC Chiral HPLC Columns (Macrocyclic Glycopeptides), Astec CHIROBIOTIC V Chiral HPLC Columns, CHIROBIOTIC V, Chiral HPLC Columns,
description   HPLC Column
packaging   pkg of 1 ea
mfr. no.   Astec
parameter   0-45 °C temperature
  241 bar pressure (3500 psi)
application(s)   HPLC: suitable
L × I.D.   10 cm × 4.6 mm
matrix   High-purity silica gel particle platform
matrix active group   vancomycin phase
particle size   5 μm
pore size   100 Å
operating pH range   3.5 - 7.0
separation technique   chiral

Description

General description

Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC® V in the polar ionic mode. The CHIROBIOTIC® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity.

• Bonded phase: Vancomycin
• Operating pH range: 3.5 - 7.0
• Particle diameter: 5, 10 or 16 μm
• Pore size: 100 Å (CHIROBIOTIC® V) or 200 Å (CHIROBIOTIC® V2)

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Legal Information

Astec is a registered trademark of Sigma-Aldrich Co. LLC

CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Chiral and Achiral LC-MS Analysis of Warfarin™ in Plasma

Clinical laboratories are beginning to reap the benefits of LC-MS in terms of its sensitivity, specificity, throughput, and potential to reduce cost per sample. The purpose of this study was to demon...
Tracy L. Ascah, and Craig R. Aurand
Reporter US Volume 31.2
Keywords: Anticoagulants, Chromatography, Clinical, Forensic, Genetic, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolism, Metabolites, Phase transitions, Precipitation, Separation, Solid phase extractions, Solvents, Vitamins

LC/MS/MS Analysis of Warfarin™ Enantiomers in Plasma on Astec® CHIROBIOTIC® V after SPE using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Warfarin™ Enantiomers in Plasma on Astec® CHIROBIOTIC® V after SPE using HybridSPE®-Phospholipid
Keywords: Anticoagulants, Chromatography, Clinical, Forensic, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Solid phase extractions, Solvents

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Peer-Reviewed Papers
15

References

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