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12010AST Supelco

Astec® CHIROBIOTIC® T Chiral HPLC Column

5 μm particle size, L × I.D. 10 cm × 3 mm

  •  eCl@ss 32110501

  •  NACRES SB.52



Related Categories Analytical/Chromatography, Astec CHIROBIOTIC Chiral HPLC Columns (Macrocyclic Glycopeptides), Astec CHIROBIOTIC T Chiral HPLC Columns, CHIROBIOTIC T, Chiral HPLC Columns,
Quality Level   100
description   HPLC column
packaging   pkg of 1 ea
mfr. no.   Astec
parameter   0-45 °C temperature
  241 bar pressure (3500 psi)
application(s)   HPLC: suitable
L × I.D.   10 cm × 3 mm
matrix   High-purity silica gel particle platform
matrix active group   teicoplanin glycopeptide phase
particle size   5 μm
pore size   100 Å
operating pH range   3.8 - 6.8
suitability   suitable for L63 per USP
separation technique   chiral


General description

CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.

• Bonded phase: Teicoplanin
• Operating pH range: 3.8 - 6.8
• Particle diameter: 5, 10 or 16 μm
• Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2)

CHIROBIOTIC Reference Bibliography
Chiral Product Literature

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Legal Information

Astec is a registered trademark of Sigma-Aldrich Co. LLC

CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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