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16124AST Supelco

Astec® CHIROBIOTIC® T2 Chiral HPLC Column

10 μm particle size, L × I.D. 25 cm × 4.6 mm

  •  eCl@ss 32110501

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Properties

Related Categories Analytical/Chromatography, Astec CHIROBIOTIC Chiral HPLC Columns (Macrocyclic Glycopeptides), Astec CHIROBIOTIC T2 Chiral HPLC Columns, CHIROBIOTIC T2, Chiral HPLC Columns,
description   HPLC column
packaging   pkg of 1 ea
application(s)   HPLC: suitable
L × I.D.   25 cm × 4.6 mm
matrix   high-purity silica gel particle platform
particle size   10 μm
pore size   200 Å
operating pH range   3.8 - 6.8
suitability   suitable for L63 per USP
separation technique   chiral

Description

General description

CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.

• Bonded phase: Teicoplanin
• Operating pH range: 3.8 - 6.8
• Particle diameter: 5, 10 or 16 μm
• Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2)

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Legal Information

Astec is a registered trademark of Sigma-Aldrich Co. LLC

CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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Documents

Certificate of Analysis


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Peer-Reviewed Papers
15

References

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