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20224AST Supelco

Astec® CYCLOBOND® I 2000 SP Chiral HPLC Column

5 μm particle size, L × I.D. 25 cm × 4.6 mm

  •  eCl@ss 32110501

  •  NACRES SB.52



Related Categories Analytical/Chromatography, Astec CYCLOBOND Chiral HPLC Columns (Native and Derivatized Cyclodextrins), CYCLOBOND I 2000 SP, Chiral HPLC Columns, HPLC Columns, by USP Code,
Quality Level   100
packaging   pkg of 1 ea
mfr. no.   Astec
parameter   0-50 °C temperature
  172 bar pressure (2500 psi)
application(s)   HPLC: suitable
L × I.D.   25 cm × 4.6 mm
matrix   silica particle platform
matrix active group   cyclodextrin, beta- phase
particle size   5 μm
pore size   100 Å
suitability   suitable for L45 per USP
separation technique   chiral


General description

On CYCLOBOND I 2000 SP, the hydroxyl groups on the surface of the β-cyclodextrin have been reacted with (S)-propylene oxide. This has the effect of extending hydrogen-bonding capabilities to accommodate analytes with chiral centers that are relatively distant from an aromatic ring structure. The (S)- form shows enhanced selectivity and efficiency for some separations, methadone, for example.

• Bonded phase: (S)-Hydroxypropyl modified β-cyclodextrin

CYCLOBOND Reference Bibliography
Chiral Product Literature

Other Notes

Recommended alternative 20024AST ASTEC® CYCLOBOND® 2000 Chiral HPLC Column
See technical report

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Legal Information

Astec is a registered trademark of Sigma-Aldrich Co. LLC

CYCLOBOND is a registered trademark of Sigma-Aldrich Co. LLC

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