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47763 Supelco

Cholecalciferol (D3)

analytical standard

Synonym: (+)-Vitamin D3, 7-Dehydrocholesterol activated, Activated 7-dehydrocholesterol, Calciol, Cholecalciferol

  • CAS Number 67-97-0

  • Empirical Formula (Hill Notation) C27H44O

  • Molecular Weight 384.64

  •  Beilstein/REAXYS Number 2339331

  •  EC Number 200-673-2

  •  MDL number MFCD00078131

  •  PubChem Substance ID 24871395

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Application Areas and Market Segments, Biochemicals and Reagents,
Quality Level   100
grade   analytical standard
form   neat
feature   standard type fat soluble vitamin
packaging   ampule of 100 mg
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
color   white
mp   83-86 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Food and Beverages
Personal Care
Pharmaceutical (small molecule)
Vitamins, Nutraceuticals, and Natural Products
format   neat
storage temp.   2-8°C
SMILES string   CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
InChI   1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key   QYSXJUFSXHHAJI-YRZJJWOYSA-N
Gene Information   human ... VDR(7421)

Description

General description

Cholecalciferol (D3) is a fat soluble vitamin, and is one of the forms of vitamin D, synthesized in human skin on exposure to ultraviolet (UV) radiation from sunlight, or it can also be obtained from food. It is found to be essential in humans for maintaining normal calcium metabolism.

Application

Cholecalciferol (D3) may be used as an analytical reference for the quantification of the analyte in different food matrices using different chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
WGK 2
RTECS 
VS2900000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

AOAC Method 2011.11: UHPLC/MS/MS Analysis of Vitamin D in Infant formula on Titan™ C18

From our library of Articles, Sigma-Aldrich presents AOAC Method 2011.11: UHPLC/MS/MS Analysis of Vitamin D in Infant formula on Titan™ C18
Keywords: High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites, Saponifications, Vitamins

AOAC Method 2011.11: UHPLC/MS/MS Analysis of Vitamin D in Milk on Titan™ C18

From our library of Articles, Sigma-Aldrich presents AOAC Method 2011.11: UHPLC/MS/MS Analysis of Vitamin D in Milk on Titan™ C18
Keywords: Chromatography, Mass spectrometry, Vitamins

AOAC Method 2011.11: UHPLC/MS/MS Analysis of Vitamin D2 and Vitamin D3 on Titan™ C18

From our library of Articles, Sigma-Aldrich presents AOAC Method 2011.11: UHPLC/MS/MS Analysis of Vitamin D2 and Vitamin D3 on Titan™ C18
Keywords: Mass spectrometry, Separation, Vitamins

Analysis of Vitamin D in Milk and Infant Formula using UHPLC/MS/MS per AOAC Method 2011.11

Fortification of milk, dairy products, infant and adult nutritionals with vitamin D is required in many countries to provide additional dietary vitamin D. The fortification of milk in the USA, for ex...
Olga Shimelis
Reporter US Volume 33.2
Keywords: Chromatography, Evaporation, High performance liquid chromatography, Mass spectrometry, Metabolites, Sample preparations, Saponifications, Separation, Solvents, Vitamins

HPLC Analysis Report of Vitamin D2 and D3 on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis Report of Vitamin D2 and D3 on Ascentis® Express C18
Keywords: Chromatography, Clinical, High performance liquid chromatography, Vitamins

HPLC Analysis of Bufalin Toxin on Discovery® BIO Wide Pore C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bufalin Toxin on Discovery® BIO Wide Pore C18
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si, 15 cm Column

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si, 15 cm Column
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Methanol Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat Soluble Vitamins on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins on Ascentis® RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamin D2 and D3 on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamin D2 and D3 on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamin D2 and Vitamin D3 on Ascentis® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamin D2 and Vitamin D3 on Ascentis® C18
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamins, Fat Soluble (D2 and D3), on Discovery® HS C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Fat Soluble (D2 and D3), on Discovery® HS C18
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamins, Fat Soluble, on Ascentis® Si

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Fat Soluble, on Ascentis® Si
Keywords: Chromatography, High performance liquid chromatography, Vitamins

LC/MS Analysis of Vitamin D2, D3, Gamma- and Alpha-Tocopherol on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Vitamin D2, D3, Gamma- and Alpha-Tocopherol on Ascentis® Express C18
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Vitamins

Peer-Reviewed Papers
15

References

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