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52783-U Supelco

Discovery® DSC-MCAX SPE Tube

bed wt. 100 mg, volume 3 mL, pk of 54

  •  NACRES NB.21

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Properties

Related Categories Analytical/Chromatography, Discovery DSC-MCAX (Mixed-Mode Cation Exchange) SPE Products, Discovery SPE Tubes, Sample Preparation & Purification, Solid Phase Extraction (SPE) More...
Quality Level   100
material   PE frit (20 μm)
  polypropylene hardware
feature   endcapped
composition   bed wt., 100 mg
packaging   pk of 54
extent of labeling   8.4% C loading
volume   3 mL
matrix   silica gel base material (irregulary shaped, acid washed)
matrix active group   C8 (octyl) bonding
  sulfonic acid bonding
particle size   50 μm
pore size   70 Å pore size
surface area   480 m2/g
capacity   0.06 meq/g capacity
Featured Industry   Food and Beverages
separation technique   mixed mode

Description

General description

Retention Mechanism: Mixed-Mode Cation Exchange (reversed-phase and cation-exchange)
Sample Matrix Compatibility: Aqueous Solutions (biological fluids, water)

• Packed bed contains both octyl (C8) & benzene sulfonic acid (SCX) bondings
• Dual retention mechanism broadens retention for a range of neutral, basic, acidic and zwitterionic compounds
• Developed for superior selectivity/ sample clean up when isolating basic compounds from biological fluids
• Greater ion-exchange capacity for isolating polar basic and zwitterionic compounds
• Can be used to fractionate basic/ zwitterionic compounds from acidic and neutral compounds

Legal Information

Discovery is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Amphetamines in Urine on Discovery® HS F5 after SPE using Discovery® DSC-MCAX and Standard C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Amphetamines in Urine on Discovery® HS F5 after SPE using Discovery® DSC-MCAX and Standard C18
Keywords: Calorimetry, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Sample preparations, Solid phase extractions

HPLC Analysis of Piroxicam and 2-Aminopyridine in Urine on Discovery® HS F5 after SPE using Discovery® DSC-MCAX

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Piroxicam and 2-Aminopyridine in Urine on Discovery® HS F5 after SPE using Discovery® DSC-MCAX
Keywords: Calorimetry, Chromatography, Clinical, High performance liquid chromatography, Metabolites, Pharmaceutical, Sample preparations, Solid phase extractions

The Importance of Ion-Exchange Capacity in Mixed-Mode SPE

Most researchers who use SPE to process biological samples rely on traditional single-mode retention mechanisms to recover, clean up, and concentrate their compounds of interest prior to LC or GC ana...
Reporter EU Volume 11
Keywords: Applications, Calorimetry, Gas chromatography, High performance liquid chromatography, Metabolism, Metabolites, Solid phase extractions, Support

Related Content

SPE Cartridges (Tubes) - Phase Selection Guide

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.
Keywords: Agriculture, Calorimetry, Environmental, Fractionation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pesticides, Pharmaceutical, Solid phase extractions

Solid Phase Extraction: Fundamentals and Recent Developments [Webinar]

Solid Phase Extraction (SPE) has become a popular technique for sample preparation due to its convenience, effectiveness, relatively low solvent usage and versatility. The focus of this webinar is on...
Keywords: Sample preparations, Solid phase extractions

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