• USA Home
  • 53210-U - SupelMIP® SPE - Chloramphenicol

53210-U Supelco

SupelMIP® SPE - Chloramphenicol

bed wt. 25 mg, volume 10 mL , LRC, pk of 50

  •  NACRES NB.21



Related Categories Analytical/Chromatography, Sample Preparation & Purification, Solid Phase Extraction (SPE), SupelMIP Molecular Imprinted Polymers, SupelMIP SPE - Chloramphenicol More...
material   polypropylene tube
composition   bed wt., 25 mg
packaging   pk of 50
volume   10 mL , LRC
matrix active group   SupelMIP® phase
Featured Industry   Food and Beverages


General description

SupelMIP SPE phases were developed by MIP Technologies AB, which is one of the leading authorities and commercial pioneers of molecular imprinted polymers for process scale separations, analytical chromatography, and sample preparation.

The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the analyte(s) of interest.

By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.

Visit www.sigma-aldrich.com/supelmip to learn more.


A MIP phase developed and optimized for the selective extraction of chloramphenicol in biological matrices.

Chloramphenicol is a broad-spectrum antibiotic that is currently banned by a number of countries including the EU, the US, and Canada. This MIP phase and associated method offer a simple, efficient, and highly selective extraction method for quantiting chloramphenicol in food products and biological matrices. Detection limits well below the minim required performance limit (MPRL) are achieved consistently.

Features and Benefits

• Highly selective SPE for trace analysis in complex matrices
• Achieve lower detection limits
• Significant time and cost savings
• Improved MS-compatibility

Legal Information

SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.


Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles


Comparison of SupelMIP™ SPE – Beta-agonists and Mixed-mode SPE for the Extraction of beta-agonists from Urine Samples

Beta-2-adrenergic receptor agonists (Beta-agonists) have been clinically used in the treatment of cardiovascular and breathing disorders in veterinary and human medicine. However, beta-agonists are a...
Olaf Heemken, Anna-Karin Whilborg
Reporter US Volume 26.4
Keywords: Agriculture, Cardiovascular, Solid phase extractions, Veterinary

HPLC Analysis of Chloramphenicol in Milk on Ascentis® C18 after SPE using SupelMIP® SPE-Chloramphenicol

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Chloramphenicol in Milk on Ascentis® C18 after SPE using SupelMIP® SPE-Chloramphenicol
Keywords: Antibiotics, Antimicrobials, Chromatography, Clinical, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Sample preparations, Solid phase extractions, Veterinary

Method Validation for Determination of Chloramphenicol in Urine Using Molecularly Imprinted Polymer (MIP) SPE

The method for determination of low concentrations of chloramphenicol in bovine and porcine urine was developed. Sample cleanup was performed by Molecular Imprinted Polymer (MIP) columns. Confirmator...
Reporter EU Volume 35
Keywords: Antibiotics, Gas chromatography, Gas chromatography mass spectrometry, High performance liquid chromatography, Mass spectrometry, Methods, Sample preparations, Silylations, Solid phase extractions, Type, Veterinary

Related Content

SPE Cartridges (Tubes) - Phase Selection Guide

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.
Keywords: Agriculture, Calorimetry, Environmental, Fractionation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pesticides, Pharmaceutical, Solid phase extractions

Solid Phase Extraction: Fundamentals and Recent Developments [Webinar]

Solid Phase Extraction (SPE) has become a popular technique for sample preparation due to its convenience, effectiveness, relatively low solvent usage and versatility. The focus of this webinar is on...
Keywords: Sample preparations, Solid phase extractions

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?