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54243-U Supelco

Supel-Select SCX SPE Tube

bed wt. 500 mg, volume 12 mL, pk of 20

  •  NACRES NB.21



Related Categories Analytical/Chromatography, SCX SPE Tubes and 96-well Plates, Sample Preparation & Purification, Solid Phase Extraction (SPE), Supel-Select SPE More...
Quality Level   100
material   PE frit (20 μm)
  polypropylene hardware
quality   MS Friendly
composition   bed wt., 500 mg
packaging   pk of 20
volume   12 mL
matrix   Sulfonic acid functionalized hydrophilic modified styrene polymer particle platform
matrix active group   sulfonic acid phase
particle size   50-70 μm
pore size   80-200 Å pore size
surface area   160-420 m2/g
Featured Industry   Food and Beverages
separation technique   ion exchange


General description

Retention Mechanism: Ion-Exchange
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)

• Sulfonic acid functionalized hydrophilic modified styrene polymer
• Developed for the extraction of a highly broad range of compounds from aqueous samples
• Retention predominately based on ion-exchange; however, because the phase is hydrophilic modified, it is amenable to polar compounds as well.

View related article: Isolation and LC-MS Characterization of Illicit Bath Salts in Urine

Features and Benefits

• Excellent sample prep performance at a lower price
• Amenable to generic methodology - save time, money, and headache during method development
• Greater capacity allows for smaller bed weights = smaller elution volumes = time savings in sample processing
• Resistance to overdrying allows for more robust methdology
• Low UV and MS extractables for lower background and greater sensitivity
• Stringent production and QC guidelines offer greater lot-to-lot, tube-to-tube, and well-to-well consistency for improved accuracy and precision

Legal Information

Supel is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.


Certificate of Analysis (COA)

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Protocols & Articles


Solid Phase Extraction: Ion Exchange Methodology

In order for electrostatic retention to occur, both analyte and sorbent functional groups must be in their ionized form. This is done through strict pH control of the sample matrix. For basic analyte...
Keywords: Agriculture, Buffers, Herbicides, Ion Exchange, Pharmaceutical, Solid phase extractions

Solid Phase Extraction: Normal Phase Methodology

In order for polar retention to occur between the sorbent and the sample, the analyte must be introduced to the SPE device in a non-polar sample or mobile phase environment. Therefore, typical sample...
Keywords: Cosmetics, Fractionation, Gas chromatography, Separation, Solid phase extractions, Solvents, Sonication

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SPE Cartridges (Tubes) - Phase Selection Guide

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.
Keywords: Agriculture, Calorimetry, Environmental, Fractionation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pesticides, Pharmaceutical, Solid phase extractions

Solid Phase Extraction: Fundamentals and Recent Developments [Webinar]

Solid Phase Extraction (SPE) has become a popular technique for sample preparation due to its convenience, effectiveness, relatively low solvent usage and versatility. The focus of this webinar is on...
Keywords: Sample preparations, Solid phase extractions

Supel™-Select Polymeric SPE [Product Overview Video]

Supel-Select HLB and Ion-Exchange phases are ideal for efficient and highly reproducible solid phase extraction of a broad range of compounds from aqueous samples. Their use covers a range of applica...
Keywords: Solid phase extractions

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