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57228-U Supelco

Discovery® DSC-WCX SPE Bulk Packing

pkg of 100 g

  •  NACRES NB.21



Related Categories Analytical/Chromatography, Discovery DSC-WCX SPE Products, Discovery SPE Tubes, Sample Preparation & Purification, Solid Phase Extraction (SPE) More...
packaging   pkg of 100 g
matrix active group   carboxypropyl bonding
Featured Industry   Food and Beverages
separation technique   ion exchange


General description

Retention Mechanism: Cation exchange
Sample Matrix Compatibility: Organic or aqueous solutions

• A polymerically bonded, ethylenediamine triacetic acid phase with a pKa of 4.8
• Counter ion is Na+
• Ion exchange capacity is ∼ 0.15 meq/g
• Carries a negative charge at pH 6.8 or above
• A pH of 2.8 or below neutralizes this phase for easier elution of strong cationic analytes that are neutralized only at extreme basic conditions
• Typically used when dealing with very strong cationic (high pKa) compounds that may be irreversibly retained on strong cation exchangers

Legal Information

Discovery is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


Solid Phase Extraction: Ion Exchange Methodology

In order for electrostatic retention to occur, both analyte and sorbent functional groups must be in their ionized form. This is done through strict pH control of the sample matrix. For basic analyte...
Keywords: Agriculture, Buffers, Herbicides, Ion Exchange, Pharmaceutical, Solid phase extractions

Solid Phase Extraction: Normal Phase Methodology

In order for polar retention to occur between the sorbent and the sample, the analyte must be introduced to the SPE device in a non-polar sample or mobile phase environment. Therefore, typical sample...
Keywords: Cosmetics, Fractionation, Gas chromatography, Separation, Solid phase extractions, Solvents, Sonication

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SPE Cartridges (Tubes) - Phase Selection Guide

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.
Keywords: Agriculture, Calorimetry, Environmental, Fractionation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pesticides, Pharmaceutical, Solid phase extractions

Solid Phase Extraction: Fundamentals and Recent Developments [Webinar]

Solid Phase Extraction (SPE) has become a popular technique for sample preparation due to its convenience, effectiveness, relatively low solvent usage and versatility. The focus of this webinar is on...
Keywords: Sample preparations, Solid phase extractions

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