• USA Home
  • 57265 - Visiprep SPE Vacuum Manifold

57265 Supelco

Visiprep SPE Vacuum Manifold

DL (Disposable Liner), 24-port model



General description

SPE is a form of chromatography, and, as with other chromatographic techniques, control of flow rate is critical for maintaining reproducible extractions. Unlike other vacuum manifolds, the Visiprep system contains a patented valve system that allows for precise flow control through each SPE tube via rotating, independent, screw-type valves situated in each port within the manifold cover. Visiprep vacuum manifolds allow you to process up to 12 (12-port version) or 24 (24-port version) SPE samples simultaneously. Spacing between ports are slightly smaller on the 24-port versions than the 12-port versions so consideration of tube sizes is recommended.

The Visiprep DL (Disposable Liner) Vacuum Manifold eliminates the possibility of cross-contamination when processing a new sample on the same port. The liner consists of a PP female luer hub that attaches to the SPE, and thin-walled PTFE tubing that is threaded through the SPE port. This ensures that all SPE port and valve surfaces coming in contact with the sample can be replaced following each extraction.


Visiprep SPE Vacuum Manifold was used to perform solid phase extraction to separate polyphenols from grapes, in order to determine the polyphenol content using LC-MS analysis. It was also used for concentration and purification of solvent extracts from surface water and sewage water sediments. Furthermore it was also used to extract and determine estrone in water using solid-phase extraction-enzyme-linked immunosorbent assay (SPE-ELISA).

Features and Benefits

Supplied with 100 disposable liners (Part No. 57059).

• Patented screw-type valves within each SPE port for precise flow control
• Glass basin will not dissolve, fog, or discolor when exposed to solvents
• Legs on cover allow user to easily rest cover on work surface when removed from the manifold
• Screw-type solvent-resistant vacuum bleed gauge and valve offer better sealing and vacuum control. Valve takes 1/4″ vacuum tubing.
• PP collection vessel rack accommodates autosampler vials; small scintillation vials (22.75 mm O.D. recommended); 10 and 16 mm test tubes; and 1, 2, 5, and 10 mL volumetric flasks. An optional plate for 20 mL scintillation vials is available for 12-port models.

Legal Information

Visiprep is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
Can I convert the Visiprep DL 24-port Manifold, Product No. 57265, to a Standard 24-port Manifold, Product No. 57250-U?
Yes, by replacing the manifold lid with Product No. 57251 or by replacing some of the DL ports to standard ports with Product No. 57032 and Product No. 57147-U
What is the maximum vacuum for the Visiprep Vacuum Manifold, Product 57265?
The maximum vacuum for the Visiprep Vacuum Manifold is 20 inches of Mercury (Hg).
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Show more questions
Protocols & Articles


Analysis of PCBs in Fish Oil

Polychlorinated biphenyls (PCBs) were once widely used in many industrial and commercial applications such as insulating fluids, dielectrics, and lubricants. This included their extensive use in elec...
Kathy Stenerson, Caitlin Brown
Reporter US Volume 33.4 (Food & Bev. Suppl.)
Keywords: Chromatography, Column chromatography, Electron capture detector, Fractionation, Gas chromatography, High performance liquid chromatography, Mass spectrometry, Sample preparations, Size-exclusion chromatography, Solid phase extractions

Bath Salts in Urine

LC-MS Analysis of Illicit Bath Salts in Urine on Ascentis Express HILIC after Solid Phase Extraction (SPE) on Supel-Select SCX
Keywords: Chromatography, Diagnostic, Forensic, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Separation, Solid phase extractions

Determination of PAHs in Paprika Powder Using a Novel SPE Cartridge

Paprika is a spice made from dried sweet peppers, and is used for flavor and color in many types of cuisine. Contamination with polynuclear aromatic hydrocarbons (PAHs) can occur when pepper plants a...
Katherine K. Stenerson
Keywords: Capillary electrophoresis, Chromatography, Gas chromatography, Mass spectrometry, Pesticides, Reductions, Sample preparations, Size-exclusion chromatography, Solid phase extractions, Solvents

QuEChERS Cleanup and Analysis of Veterinary Drugs in Milk by LC/MS/MS

The use of mass spectrometry (MS) as an analytical technique allows quick screening, identification, and confirmation of contaminants. In spite of advances that MS instrumentation brings to achieve e...
Olga I. Shimelis, and Jennifer Claus
Reporter US Volume 34.1
Keywords: Antibiotics, Calorimetry, Environmental, High performance liquid chromatography, Mass spectrometry, Pesticides, Phase transitions, Sample preparations, Separation, Solid phase extractions, Veterinary

UHPLC/MS of Drugs and Metabolites in Urine following Enzymatic Hydrolysis

β-D-Glucuronide glucuronosohydrolase enzymes, commonly shortened to β-glucuronidase, play an important role in the analysis of biological fluids for the presence of metabolites for drug screening and...
Craig Aurand, Manager; Kristen Brown, Pennsylvania State University
Reporter US Volume 33.2
Keywords: Carbohydrate metabolism, Derivatizations, Digestions, Enzyme activity, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolism, Metabolites, Sample preparations, Separation, Solid phase extractions, Solvents

Related Content

SPE Cartridges (Tubes) - Phase Selection Guide

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.
Keywords: Agriculture, Calorimetry, Environmental, Fractionation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pesticides, Pharmaceutical, Solid phase extractions

Peer-Reviewed Papers


Related Products

related product

Product #


Add to Cart

Z255998 Gum rubber laboratory tubing, tubing I.D. × O.D. 1/4  in. × 1 in.
57027 Visiprep DL (Disposable Liner) Replacement Liner Guide Needles (included with 57044 and 57265), for use with DL (Disposable Liner), 12- and 24-port models, stainless steel, pk of 12
57035-U SPE Manifold Gauge/Bleed Valve, for use with Visiprep 12-port and 24-port models
57041 Retaining Clips For Visiprep SPE Manifold Collection Racks, included with standard and DL, 12- and 24-port models, pk of 12
57059 Disposable Liners for Visiprep DL Manifolds (included with 57044 and 57265), PTFE, pk of 100
57254 Visiprep Manifold Replacement Gasket, for use with 24-port model (standard and DL), pk of 2
57255 Visiprep Manifold Collection Rack (included with standard and DL models), for use with 24-port model, includes base, 2 support rods, center plate, plate for 10 mm test tubes, 8 retaining clips
57257 Visiprep Manifold Plate (included with standard and DL models unless otherwise noted), for use with 24-port model, 16 mm test tubes
57266 Visiprep Manifold Cover (flow control valves and gasket included), for use with DL (Disposable Liner), 24-port model
57028 Visiprep Manifold Flow Control Valve, for use with DL (Disposable Liner) 12- and 24-port models, pk of 2
57258 Visiprep Manifold Plate (included with standard and DL models unless otherwise noted), for use with 24-port model, 2 mL autosampler vials
57146-U Visiprep Manifold Replacement Flow Control Valve Stem, for use with DL (Disposable Liner) 12- and 24-port models, pk of 24

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?