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577120-U Supelco

Titan C18 UHPLC Column, 1.9 micron

1.9 μm particle size, L × I.D. 2 cm × 2.1 mm

  •  NACRES SB.52

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Properties

Related Categories Analytical/Chromatography, HPLC Columns, by Brand for Small Molecules, HPLC/UHPLC, Titan C18 UHPLC Columns, 1.9 μm
Quality Level   100
feature   endcapped
mfr. no.   Titan
extent of labeling   13% carbon loading
parameter   18000 psi pressure (1241 bar)
  60 °C max. temp.
application(s)   HPLC: suitable
L × I.D.   2 cm × 2.1 mm
matrix   monodisperse silica particle platform
matrix active group   C18 (octadecyl) phase
particle size   1.9 μm
pore size   0.76 cm3/g pore volume
  80 Å pore size
surface area   410 m2/g
pH range   2 - 8
suitability   suitable for L1 per USP
separation technique   reversed phase

Description

General description

Titan C18 UHPLC Column (L × I.D. 2 cm × 2.1 mm):
• Delivers an efficiency > 250,000 N/m, comparable to leading UHPLC columns.
• Narrow particle size distribution translates to rugged, reliable performance.

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Legal Information

Titan is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
When are additional phases expected for Titan 1.9μm columns?
Additional Titan 1.9μmphases are being developed and will encompass all aspects of UHPLC requirements.
Are guard columns available forTitan 1.9 μm C18 columns with 2.1 mm ID?
Guard columns for Titan 1.9 μm C18 UHPLC columns with 2.1 mm ID are product 577127-U.This product is a pack of three guard cartridges with dimensions 2.1 X 5 mm.These cartridges require the use of the guard column holder, product 577133-U.
Can I use Titan 1.9 μm columns on HPLC systems?
Titan 1.9 μm columns are designed to be used only on UPLC or UHPLC systems.
Which UHPLC Instruments can be used with Titan?
Titan 1.9μm columns can be used on any UPLC or UHPLC System.
What is the best practice for long-term storage of Titan C18 1.9 μm columns?
Long-term storage of silica-based, reversed-phase columns is best in 100% acetonitrile. Columns may be safely stored for short periods (up to 3 or 4 days) in most common mobile phases. However, when using buffers, it is best to protect both the column and the HPLC equipment and remove any salts by flushing the column with the same mobile phase without the buffer (e.g., when using 60:40 ACN:buffer, flush the column with 60:40 ACN:H2O) to eliminate any danger of corrosion from the salts while providing rapid reequilibration of the column with the original mobile phase. Before storing the column, the end-fittings should be tightly sealed with the end-plugs that are provided with the column to prevent the packing from drying.
What solvents are compatible with Titan C18 1.9 μm columns?
Water and all common organic solvents are compatible with Titan C18 1.9 μm columns.
Can the Titan 1.9 μm columns be reversed for column cleaning?
Direction of flow is marked on the column label for optimum performance.Column operation with flow in the direction opposing the arrow may produce reduced performance.However, reversed flow may be used to attempt removal of inlet frit plugging or contamination.
What sets Titan UHPLC columns apart from other manufacturers' sub 2 micron particle UHPLC columns?
The patent pending Ecoporous manufacturing process, which is the basis for the Titan stationary phase, revolutionizes high purity silica production. The end result is a highly efficient column at a remarkable value.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
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Protocols & Articles

Articles

HPLC Analysis of Water-Soluble Vitamins Using Titan C18 Column

Vitamins are important compounds and are essential for normal metabolism. They are naturally found in many foods and are often added to processed food products. Water soluble vitamins include such co...
Olga Shimelis
Reporter US Volume 33.1
Keywords: High performance liquid chromatography, Metabolism, Sample preparations, Separation, Vitamins

Mycotoxin Analysis in Food and Feed: Detecting the Fungus Among Us

Mycotoxin production by various fungi on food and feed crops is an ever-present danger that requires regular and reliable analytical testing.  The ubiquitous presence of fungi in our fields, combined...
Keywords: Gas chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites, Separation, Solid phase extractions, Solvents

UHPLC Analysis of Taxanes Using A Titan C18 Column and UV Detection

Taxanes are diterpenes produced by the plants of the genus Taxus (yews), and are widely used as chemotherapy agents. Taxane agents include paclitaxel (Taxol) and docetaxel (Taxotere). The role of tax...
Keywords: Alzheimer Disease, Antitumor agents, Cancer, Chromatography, Clinical, Drug discovery, High performance liquid chromatography, Medicinal chemistry, Oncology, Pharmaceutical, Reductions, Separation

UHPLC/MS Analysis of Diazepam and Metabolites on Titan™ C18, Comparison of Flow Rate and Column Length

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Diazepam and Metabolites on Titan™ C18, Comparison of Flow Rate and Column Length
Keywords: Anti-depressants, Anticonvulsants, Chromatography, Solvents

Related Content

Supelco HPLC Calculator for Isocratic or Gradient Method Transfer

Calculates conditions for transfer of an isocratic or gradient method from one HPLC column to another. Allows method scaling from microbore through preparative column range. Calculates time and solve...
Keywords: High performance liquid chromatography

Peer-Reviewed Papers
15

References

Related Products

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Description

Add to Cart

577127-U Titan C18 UHPLC Guard Cartridge, 1.9 micron, 1.9 μm particle size, L × I.D. 5 mm × 2.1 mm, pkg of 3 ea
577133-U Titan UHPLC Guard Cartridge Holder, for use with Titan Guard Cartridges, pkg of 1 ea

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