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  • 73035AST - Astec® CHIRALDEX® G-TA Capillary GC Column

73035AST Supelco

Astec® CHIRALDEX® G-TA Capillary GC Column

L × I.D. 50 m × 0.25 mm, df 0.12 μm

  •  NACRES SB.54



Related Categories All Gas Chromatography Columns, Analytical/Chromatography, Astec CHIRALDEX G-TA, Capillary GC Columns, Capillary GC Columns, by name,
Quality Level   100
material   fused silica
description   GC capillary column
packaging   pkg of 1 ea
parameter   -10-180 °C temperature (isothermal or programmed)
Beta value   500
df   0.12 μm
application(s)   gas chromatography (GC): suitable
L × I.D.   50 m × 0.25 mm
matrix active group   non-bonded; 2,6-di-O-pentyl-3-trifluoroacetyl derivative of γ-cyclodextrin phase
Featured Industry   Agriculture
Chemicals and Industrial Polymers
Cleaning Products
Flavors and Fragrances
Food and Beverages
Forensics and Toxicology
Life Science and Biopharma
Personal Care
Pharmaceutical (small molecule)
column type   capillary chiral
separation technique   chiral


General description

Astec® CHIRALDEX G-TA is the first choice in the Group 1 CSPs (Surface Interactions, Complex Derivatives). This phase has been shown to be the most broadly-selective phase for the pharmaceutical industry, especially for the analysis of chiral intermediates and drug studies in various stages of clinical trials. Separations occur without the inclusion mechanism and are typically faster and more efficient than most chiral stationary phases. G-TA has also been used to separate parent drug enantiomers and their metabolites. G-TA has its highest selectivity for oxygen-containing analytes like alcohols, diols and polyols as the free alcohol and as an acyl derivative; amines as acyl derivatives; amino alcohols, halogens (Cl>Br>F), amino acids, hydroxy acids, lactones, furans and pyrans. It is also highly selective for halogenated compounds.

Chem/Phys Resistance

Temp. Limits:
• -10 °C to 180 °C isothermal and programmed

Other Notes

Complementary products:
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Legal Information

Astec is a registered trademark of Sigma-Aldrich Co. LLC

CHIRALDEX is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the regeneration procedure for Chiraldex TA columns?
The regeneration procedure for ChiraldexTA columns is located in Supelco brochure, T407123 (JCH), A Guide to Using Cyclodextrin Bonded Phases for Chiral Separations by Capillary Gas Chromatography, on pages 8 and 9. These pages are attached.
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Protocols & Articles


Astec® CHIRALDEX® Column Selection

Certain phases are more selective for given molecular structures. While many compounds can be enantiomerically resolved on multiple Astec CHIRALDEX phases, often an advantage can be found in selectiv...
Keywords: Chiral chromatography, Chromatography, Clinical, Derivatizations, Gas chromatography, Metabolites, Pharmaceutical, Separation

Chiral GC Analysis of Carvone Enantiomers in Essential Oils

D-Carvone and L-carvone are enantiomeric compounds that have very different smells. These mirror image compounds provide very different aroma notes. D-Carvone is the major compound found in caraway s...
Leonard M. Sidisky
Reporter US Volume 32.1
Keywords: Flame ionization detector, Gas chromatography, Separation, Size-exclusion chromatography

Proline Derivatization and Enantioresolution by Chiral GC

Amino acids are building blocks of peptides and proteins. Enantiomeric separation of these molecules can be performed through chromatography by chiral stationary phases. This article describes the ch...
Katherine K. Stenerson, Jauh-Tzuoh Lee
Reporter US Volume 26.3
Keywords: Acetylations, Building blocks, Chromatography, Derivatizations, Gas chromatography, High performance liquid chromatography, Methods, Methylations, Racemizations, Separation

Related Content

How to Choose a Capillary GC Column

An optimized chromatographic separation begins with the column. The selection of the proper capillary column for any application should be based on four significant factors:
How to Choose a Capillary GC Column
Keywords: Chromatography, Condensations, Gas chromatography, Immobilization, Mass spectrometry, Pesticides, Separation, Size-exclusion chromatography, Solid phase microextractions, Solvents, Vaporization

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