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Pentafluoropropionic anhydride

Synonym: 2,2,3,3,3-pentafluoro-a-propanol, Boron trichloride/methanol, Melatonin and related acyl tryptamines, PFPA, Perfluoropropionic anhydride, pentafluoropropionic anhydride (PFPA)

  • CAS Number 356-42-3

  • Linear Formula (CF3CF2CO)2O

  • Molecular Weight 310.05

  •  Beilstein Registry Number 1806446

  •  EC Number 206-604-2

  •  MDL number MFCD00000429

  •  PubChem Substance ID 329775301

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Properties

grade   for GC (ECD)
  for GC derivatization (GC/GC-MS)
  for GC/MS (SIM)
description   Acylation reagent
InChI Key   XETRHNFRKCNWAJ-UHFFFAOYSA-N
packaging   pkg of 10 × 1 mL (33167)
  pkg of 1 × 25 mL (33168)
bp   69-70 °C/735 mmHg(lit.)
density   1.571 g/mL at 25 °C(lit.)
reaction suitability   reagent type: derivatization reagent
reaction type: Acylations
  reagent type: derivatization reagent
reaction type: Esterifications

Description

Application

Suitable for the derivatization of amines, Υ-aminobutyric acid, biogenic amines, anilines, amino acid, Υ-glutanyl amino acids, dopamine, 3,4-dihydroxyphenylacetic acid, dipeptides, homovanillic acid, indole alkyl amine, mefenamic acid, acidic metabolites of catecholamines and tryptamines, methylphenidate, and phenolic carboxylic acids.

Other Notes

Reagent for 1-chloro-1,1,3,3,3-pentafuoro-2-propyl ester, hexafluoroisopropyl ester, N-pentafluoropropionyl, methyl ester, pentafluoropropionate and pentafluoropropionyl (PFP), and pentafluoropropyl ester.

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
Reacts violently with water.
RIDADR 
UN 3265 8 / PGII
WGK Germany 
3
Protocols & Articles
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