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1012780 USP

Alendronate sodium

United States Pharmacopeia (USP) Reference Standard

Synonym: 4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid, monosodium, Alendronate sodium trihydrate, MK-217

  • CAS Number 121268-17-5

  • Empirical Formula (Hill Notation) C4H12NaNO7P2 · 3 H2O

  • Molecular Weight 325.12

  •  MDL number MFCD01748233

  •  PubChem Substance ID 329748953

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards A - B More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   USP
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   [Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
InChI   1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
InChI key   DCSBSVSZJRSITC-UHFFFAOYSA-M
Gene Information   human ... FDPS(2224)

Description

General description

Alendronate sodium is a primary amino bisphosphonate.

Biochem/physiol Actions

Alendronate sodium trihydrate is a bone resorption inhibitor; farnesyl diphosphate synthase inhibitor (IC50 = 460 nM); CD45 protein tyrosine phosphatase inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
SZ6523500
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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PHR1599 Alendronate Sodium, Pharmaceutical Secondary Standard; Certified Reference Material

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