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1012917 USP

Alfuzosin hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym: N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride, Uroxatral hydrochloride

  • CAS Number 81403-68-1

  • Empirical Formula (Hill Notation) C19H27N5O4 · HCl

  • Molecular Weight 425.91

  •  MDL number MFCD00879135

  •  PubChem Substance ID 329748956

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards A - B More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   USP
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   Cl.COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3
InChI   1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H
InChI key   YTNKWDJILNVLGX-UHFFFAOYSA-N
Gene Information   human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Alfuzosin hydrochloride is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Alfuzosin USP Monograph – HPLC method for Related Substances

Alfuzosin is an antagonist of the α1 adrenergic receptor and it relaxes the muscles in the prostate and bladder neck, making it easier to urinate. It is used to treat benign prostatic hyperplasia (BP...
Keywords: High performance liquid chromatography

Peer-Reviewed Papers
15

References

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PHR1638 Alfuzosin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

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