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1019701 USP

Amiloride hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym: N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate, Amiloride hydrochloride dihydrate

  • CAS Number 17440-83-4

  • Empirical Formula (Hill Notation) C6H8ClN7O · HCl · 2H2O

  • Molecular Weight 302.12

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards A - B More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   USP
Featured Industry   Pharmaceutical (small molecule)
format   neat
InChI   1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2
InChI key   LTKVFMLMEYCWMK-UHFFFAOYSA-N

Description

General description

Amiloride hydrochloride is a photosensitive yellow powder used as a mild diuretic drug.

Application

It was used as a calibration standard, during a study performed for simultaneous analysis of synthetic samples and commercial tablet preparations containing hydrochlorothiazide (HCT) and amiloride hydrochloride (AMH), using spectrophotometric analysis and comparing with HPLC data.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

UHPLC/MS/MS Analysis of 25 Small Molecule Pharmaceutical Compounds on Ascentis® Express RP-Amide

From our library of Articles, Sigma-Aldrich presents UHPLC/MS/MS Analysis of 25 Small Molecule Pharmaceutical Compounds on Ascentis® Express RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Separation

Peer-Reviewed Papers
15

References

Related Products

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PHR1839 Amiloride Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

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