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1043003 USP

Ascorbic acid

United States Pharmacopeia (USP) Reference Standard

Synonym: L-Ascorbic acid, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

  • CAS Number 50-81-7

  • Empirical Formula (Hill Notation) C6H8O6

  • Molecular Weight 176.12

  •  Beilstein/REAXYS Number 84272

  •  EC Number 200-066-2

  •  MDL number MFCD00064328

  •  PubChem Substance ID 329749065

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards A - B More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   USP
mp   190-194 °C (dec.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
InChI   1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChI key   CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Description

General description

Ascorbic acid (AA) is also know as vitamin C. It is present in plant tissues, helps in active growth and has has antioxidant property. It is easily oxidized in aqueous solutions and is favored by oxygen and by heavy metal ions.

Application

It was used as standard during the determination of ascorbic acid in lymphocytes using HPLC.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Assay and Organic Impurity Profiling of Droxidopa using a ZIC-HILIC column and UV detection

Droxidopa is a synthetic amino acid precursor, and acts as a prodrug to norepinephrine (noradrenaline) to increase neurotransmitter concentration in the body and the brain. Droxidopa was developed by...
Keywords: High performance liquid chromatography, Neurotransmitters, Pharmaceutical

HPLC Analysis of Ascorbic Acid in White Wine: Scaling Separations from Analytical to Semi-Preparative on SeQuant ZIC-HILIC, 4.6 mm to 20 mm I.D. Columns

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ascorbic Acid in White Wine: Scaling Separations from Analytical to Semi-Preparative on SeQuant ZIC-HILIC, 4.6 mm to 20 mm I.D. Columns
Keywords: High performance liquid chromatography

HPLC Analysis of Vitamins, Water Soluble, on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble, on Ascentis® RP-Amide
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of an Energy Drink on Ascentis® Express HILIC, 10 cm (UV Detection)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of an Energy Drink on Ascentis® Express HILIC, 10 cm (UV Detection)
Keywords: Chromatography, High performance liquid chromatography

TLC Analysis of Ingredients in Anti-Influenza Agents on HPTLC Silica Gel 60 RP-18 WF 254s with concentrating zone (analyte set 1)

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Ingredients in Anti-Influenza Agents on HPTLC Silica Gel 60 RP-18 WF 254s with concentrating zone (analyte set 1)
Keywords: Thin layer chromatography

Peer-Reviewed Papers
15

References

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PHR1008 Ascorbic Acid, Pharmaceutical Secondary Standard; Certified Reference Material
08168 Timestrip Plus 8 °C

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