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1118000 USP

Chloroquine phosphate

United States Pharmacopeia (USP) Reference Standard

Synonym: N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt, Chloroquine diphosphate salt

  • CAS Number 50-63-5

  • Empirical Formula (Hill Notation) C18H26ClN3 · 2H3PO4

  • Molecular Weight 515.86

  •  Beilstein/REAXYS Number 4223142

  •  MDL number MFCD00069852

  •  PubChem Substance ID 329749320

  •  NACRES NA.24



Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards C - D More...
grade   pharmaceutical primary standard
mfr. no.   USP
mp   200 °C (dec.) (lit.)
Featured Industry   Pharmaceutical (small molecule)
SMILES string   OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI   1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)


General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

NONH for all modes of transport


Certificate of Analysis (COA)

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Protocols & Articles


Chloroquine Phosphate HPLC Assay and Impurity Profiling Methods Following the USP Monograph

A rapid, accurate, and simple method was implemented for the total chromatographic purity analysis of Chloroquine Phosphate by High Performance Liquid Chromatography with a Diode Array Detector. The ...
Keywords: Chromatography, High performance liquid chromatography, Separation

HPLC Analysis of Chloroquine Enantiomers on Astec® CHIROBIOTIC® V

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Chloroquine Enantiomers on Astec® CHIROBIOTIC® V
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

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PHR1258 Chloroquine phosphate, Pharmaceutical Secondary Standard; Certified Reference Material
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